                         SEQUENCE LISTING

<110>  CADILA  HEALTHCARE  LIMITED
       BAHEKAR, Rajesh
       JAIN, Mulkul R.
       PATEL, Pankaj R.
 
<120>  SHORT  CHAIN  PEPTIDOMIMETICS  BASED  ORALLY  ACTIVE  GLP-1  
       AGONIST  AND  GLUCAGON  RECEPTOR  ANTAGONIST

<130>  2462-MUM-09

<150>  2462/MUM/2009
<151>  2009-10-22

<160>  228   

<170>  PatentIn version 3.5

<210>  1
<211>  29
<212>  PRT
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  This is N-terminal of GLUCAGON peptide

<220>
<221>  misc_feature
<222>  (29)..(29)
<223>  This is C-terminal of GLUCAGON peptide

<400>  1

His Ser Gln Gly Thr Phe Thr Ser Asp Tyr Ser Lys Tyr Leu Asp Ser 
1               5                   10                  15      


Arg Arg Ala Gln Asp Phe Val Gln Trp Leu Met Asn Thr 
            20                  25                  


<210>  2
<211>  30
<212>  PRT
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(1)
<223>  This is N-terminal of GLP-1 (7-36) peptide

<220>
<221>  misc_feature
<222>  (30)..(30)
<223>  This is C-terminal of GLP-1 (7-36) peptide

<400>  2

His Ala Glu Gly Thr Phe Thr Ser Asp Val Ser Ser Tyr Leu Glu Gly 
1               5                   10                  15      


Gln Ala Ala Lys Glu Phe Ile Ala Trp Leu Val Lys Gly Arg 
            20                  25                  30  


<210>  3
<211>  9
<212>  PRT
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(9)
<223>  These are First N-terminal 1-9 residues of GLP-1 peptide

<400>  3

His Ala Glu Gly Thr Phe Thr Ser Asp 
1               5                   


<210>  4
<211>  9
<212>  PRT
<213>  Homo sapiens


<220>
<221>  misc_feature
<222>  (1)..(9)
<223>  These are First N-terminal 1-9 residues of Glucagon peptide

<400>  4

His Ser Gln Gly Thr Phe Thr Ser Asp 
1               5                   


<210>  5
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  5

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  6
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  6

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  7
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  7

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  8
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  8

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  9
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopentane 
       carboxylic acid which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  9

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  10
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopropane 
       carboxylic acid which structurally mimics alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  10

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  11
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  11

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  12
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  12

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  13
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  13

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  14
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  14

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  15
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopentane 
       carboxylic acid which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  15

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  16
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopropane 
       carboxylic acid which structurally mimics alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  16

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  17
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  17

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  18
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  18

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  19
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  19

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  20
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  20

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  21
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  21

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  22
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  22

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  23
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  23

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  24
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  24

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  25
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  25

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  26
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  26

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  27
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  27

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  28
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  28

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  29
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  29

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  30
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  30

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  31
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  31

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  32
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  32

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  33
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  33

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  34
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  34

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  35
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  35

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  36
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  36

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  37
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  37

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  38
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  38

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  39
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  39

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  40
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  40

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  41
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  41

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  42
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  42

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  43
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  43

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  44
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  44

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  45
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  45

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  46
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  46

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  47
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  47

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  48
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  48

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  49
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  49

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  50
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  50

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  51
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  51

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  52
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  52

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  53
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  53

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  54
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  54

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  55
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  55

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  56
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  56

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  57
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  57

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  58
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  58

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  59
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  59

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  60
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  60

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  61
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  61

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  62
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  62

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  63
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  63

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  64
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  64

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  65
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  65

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  66
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  66

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  67
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  67

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  68
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  68

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  69
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  69

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  70
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  70

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  71
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  71

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  72
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  72

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  73
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  73

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  74
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  74

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  75
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  75

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  76
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  76

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  77
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  77

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  78
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  78

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  79
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  79

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  80
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  80

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  81
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  81

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  82
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  82

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  83
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  83

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  84
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  84

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  85
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopentane 
       carboxylic acid which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  85

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  86
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopropane 
       carboxylic acid which structurally mimics alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  86

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  87
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  87

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  88
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  88

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  89
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  89

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  90
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  90

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  91
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  91

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  92
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  92

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  93
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  93

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  94
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  94

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  95
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  95

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  96
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  96

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  97
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  97

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  98
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  98

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  99
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  99

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  100
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  100

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  101
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  101

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  102
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  102

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  103
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  103

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  104
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  104

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  105
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  105

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  106
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  106

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  107
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  107

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  108
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  108

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  109
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  109

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  110
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  110

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  111
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  111

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  112
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  112

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  113
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  113

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  114
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  114

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  115
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  115

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  116
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  116

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  117
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  117

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  118
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  118

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  119
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  119

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  120
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  120

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  121
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  121

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  122
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  122

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  123
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  123

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  124
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  124

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  125
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  125

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  126
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  126

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  127
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  127

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  128
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  128

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  129
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  129

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  130
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       2'-Ethyl-4'-methoxy-biphenylalanine (Bip(OMe)) which structurally
       mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  130

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  131
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  131

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  132
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  132

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  133
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  133

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  134
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  134

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  135
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopentane 
       carboxylic acid which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  135

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  136
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is 1-Amino-cyclopropane 
       carboxylic acid which structurally mimics alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  136

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  137
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  137

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  138
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  138

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  139
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  139

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  140
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  140

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  141
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  141

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  142
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  142

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  143
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  143

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  144
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  144

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  145
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  145

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  146
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  146

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  147
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  147

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  148
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  148

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  149
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  149

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  150
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  150

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  151
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  151

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  152
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  152

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  153
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  153

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  154
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  154

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  155
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  155

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  156
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  156

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  157
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  157

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  158
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  158

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  159
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  159

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  160
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  160

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  161
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  161

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  162
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  162

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  163
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  163

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  164
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  164

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  165
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  165

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  166
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  166

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  167
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  167

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  168
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  168

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  169
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  169

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  170
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  170

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  171
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  171

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  172
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  172

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  173
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  173

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  174
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  174

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  175
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  175

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  176
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  176

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  177
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  177

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  178
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  178

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  179
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  179

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  180
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (9)..(9)
<223>  Modified residue at this position is Alpha-methyl-serine 
       (alpha-Me-Ser) which structurally mimics Serine

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  180

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  181
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  181

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  182
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  182

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  183
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  183

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  184
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  184

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  185
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  185

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  186
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  186

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  187
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  187

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  188
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  188

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  189
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  189

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  190
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  190

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  191
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  191

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  192
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  192

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  193
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  193

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  194
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  194

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  195
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  195

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  196
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  196

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  197
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  197

Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  198
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  198

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  199
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  199

Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  200
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  200

Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  201
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  201

Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  202
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  202

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  203
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  203

Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  204
<211>  12
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (3)..(3)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (7)..(7)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (10)..(10)
<223>  Modified residue at this position is Alpha-methyl-aspartic acid 
       (alpha-Me-Asp) which structurally mimics aspartic acid

<220>
<221>  misc_feature
<222>  (11)..(11)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2-amino-5-phenylpentanoic acid (alpha-Me-APPA) which
       structurally mimics Phenylalanine

<400>  204

Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10          


<210>  205
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  205

Val Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  206
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  206

Val Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  207
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  207

Val Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  208
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  208

Val Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  209
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  209

Val Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  210
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  210

Val Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  211
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  211

Val Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  212
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  212

Val Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  213
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  213

Val Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  214
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  214

Val Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  215
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  215

Val Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  216
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  216

Val Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  217
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  217

Val Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  218
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  218

Val Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  219
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  219

Val Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  220
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2-flurophenylalanine (alpha-Me-2F-Phe) which 
       structurally mimics Phenyl alanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  220

Val Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  221
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  221

Val Val His Ser Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  222
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  222

Val Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  223
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  223

Val Val His Ala Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  224
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe) 
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanine

<400>  224

Val Val His Pro Gln Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  225
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  225

Val Val His Ser Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  226
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  226

Val Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  227
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-amino-isobutyric acid 
       (Aib) which structurally mimics Alanine

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  227

Val Val His Ala Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


<210>  228
<211>  13
<212>  PRT
<213>  Artificial

<220>
<223>  This peptidomimetic was synthetically generated and prepared


<220>
<221>  misc_feature
<222>  (4)..(4)
<223>  Modified residue at this position is Alpha-methyl-Proline 
       (alpha-Me-Pro) which structurally mimics Proline

<220>
<221>  misc_feature
<222>  (8)..(8)
<223>  Modified residue at this position is 
       Alpha-methyl-2,6-diflurophenylalanine (alpha-Me-2,6-diF-Phe)   
       which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (12)..(12)
<223>  Modified residue at this position is 
       Alpha-methyl-2'-Ethyl-4'-methoxy-biphenylalanine 
       (alpha-Me-Bip(OMe)) which structurally mimics Phenylalanine

<220>
<221>  misc_feature
<222>  (13)..(13)
<223>  Modified residue at this position is 2-Amino-5-phenylpentanoic 
       acid (APPA) which structurally mimics Phenylalanin

<400>  228

Val Val His Pro Glu Gly Thr Phe Thr Ser Asp Phe Phe 
1               5                   10              


